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What is the difference between API and pharmaceutical intermediates? The main difference between the two is that the API is an active product that has completed the synthesis route, and the intermediate is a product in a certain place in the synthesis route.

Custom synthesis of intermediates

We have known the difference between the API and pharmaceutical intermediates series, and now it’s time to know how APIs are produced. This production process usually includes custom synthesis services. We will elaborate on the synthesis of intermediates to uncovers this production process.

Fine Chemicals, Intermediates and Excipient

The basic principle for definition of the term. Fine Chemicals is a three-tier segmentation of the universe of chemicals into commodities, fine chemicals, and specialty chemicals

Fine chemicals are complex, single, pure chemical substances. They are produced in limited quantities (<1000 metric tons per year) in multipurpose plants by multistep batch chemical or biotech(nological) processes.

Pharmaceutical intermediates are chemical compounds which form the building blocks of the active pharmaceutical ingredient (API).

Pharmaceutical intermediates are produced as a by-product during the production of API. Every reaction in the production process of API gives rise to various different pharmaceutical intermediates. Pharmaceutical intermediates are used in the production of bulk drugs and also for research and development purpose by various pharma and biopharma companies.

The pharmaceutical industry is ever thirsty to satisfy patient’s therapeutically needs and apart from active ingredients, inactive excipients play a major role in formulation development. Pharmaceutical excipients are substances other than the pharmacologically active drug or prodrug which are included in the manufacturing process or are contained in a finished

pharmaceutical product dosage form.