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Vigore 100 is generally considered effective for treating ED. It helps improve erectile function, especially in men who may have moderate to severe ED. However, the medication needs sexual stimulation to work—it doesn’t cause an erection on its own. By inhibiting this enzyme, Vigore 100 allows blood vessels in the penis to relax and expand, increasing blood flow and making it easier to achieve and maintain an erection. The effects last for 4 to 6 hours, during which time an erection can be maintained with sexual stimulation.