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Cephalexin capsules, an antibiotic used to treat bacterial infections, typically stay in your system for about 6 to 12 hours per dose. With a half-life of approximately 1 hour, cephalexin capsules are mostly eliminated within 8 hours after the last dose, though traces may linger for up to 48 hours in some cases. Factors like kidney function, age, and dosage can affect how long cephalexin capsules remain in your body. For complete clearance, it generally takes around 5 to 6 half-lives, or roughly 5 to 6 hours, but always consult your doctor for personalized advice.